Lysyl oxidase-mediated VEGF-induced differentiation and angiogenesis in human dental pulp cells.
W-J BaeJ-K YiJ ParkS-K KangJ-H JangEun-Cheol KimPublished in: International endodontic journal (2017)
Recombinant human vascular endothelial growth factor promoted cell growth, odontogenic potential and in vitro angiogenesis via modulation of LOX expression. These results support the concept that rhVEGF may offer therapeutic benefits in regenerative endodontics.
Keyphrases
- vascular endothelial growth factor
- endothelial cells
- high glucose
- recombinant human
- induced apoptosis
- stem cells
- poor prognosis
- cell cycle arrest
- mesenchymal stem cells
- cell therapy
- binding protein
- drug induced
- endoplasmic reticulum stress
- oxidative stress
- cell death
- pluripotent stem cells
- risk assessment
- human health