Efficacy and safety of human umbilical cord-derived mesenchymal stem cells (hUC-MSC PLEB001) for the treatment of grade II-IV steroid-refractory acute graft-versus-host disease: a study protocol for a multicenter, randomized, double-blind, placebo-controlled, phase II trial.
Donglin YangXiaoqiang HouKun QianYuhang LiLiangding HuLiang LiMingzhe HanChen YaoDai-Hong LiuPublished in: Trials (2023)
Chinese Clinical Trial Registry (ChiCTR), ChiCTR2000035740. Registered on 16 August 2020.
Keyphrases
- double blind
- placebo controlled
- clinical trial
- umbilical cord
- mesenchymal stem cells
- phase ii
- phase iii
- phase ii study
- endothelial cells
- study protocol
- liver failure
- open label
- respiratory failure
- induced pluripotent stem cells
- drug induced
- combination therapy
- squamous cell carcinoma
- radiation therapy
- intensive care unit
- pluripotent stem cells
- randomized controlled trial
- rectal cancer