Login / Signup

Can the Help Match the Hype? KRASG12C-Specific Inhibitors and Beyond.

Samuel J KlempnerAaron N Hata
Published in: Cancer discovery (2020)
Hallin and colleagues demonstrate the preclinical activity of the KRASG12C-specific inhibitor MRTX849 in a series of in vitro and in vivo studies with supporting pilot clinical efficacy. Variable responsiveness despite effective KRASG12C inhibition highlights both the promise and potential need for combinatorial strategies to optimally target KRASG12C-driven cancers.See related article by Hallin et al., p. 54.
Keyphrases
  • big data
  • randomized controlled trial
  • mesenchymal stem cells
  • case control
  • young adults
  • risk assessment
  • artificial intelligence
  • deep learning