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Depressive psychopathology in first-episode schizophrenia spectrum disorders: a systematic review, meta-analysis and meta-regression.

Sarah E HernimanKelly AllottLisa J PhillipsStephen J WoodJacqueline UrenSumudu R MallawaarachchiSue M Cotton
Published in: Psychological medicine (2019)
At least one-quarter of individuals with FES will experience, and therefore require treatment for, a full-threshold depressive disorder. Nearly half will experience levels of depressive symptoms that are severe enough to warrant diagnostic investigation and therefore clinical intervention - regardless of whether they actually fulfil diagnostic criteria for a depressive disorder. Depressive psychopathology is prominent in FES, manifesting not only as superimposed comorbidity, but also as an inextricable symptom domain.
Keyphrases
  • bipolar disorder
  • depressive symptoms
  • stress induced
  • systematic review
  • randomized controlled trial
  • social support
  • meta analyses
  • case control