Clinical Outcomes for Patients With Monomicrobial vs Polymicrobial Acinetobacter baumannii-calcoaceticus Complex Infections Treated With Sulbactam-Durlobactam or Colistin: A Subset Analysis From a Phase 3 Clinical Trial.

Sarah M McLeod Alita A MillerKhurram RanaDavid AltaracSamir H Moussa Adam B Shapiro

Published in: Open forum infectious diseases (2024)

These results suggest that the use of sulbactam-durlobactam plus a carbapenem could be an effective approach to treat polymicrobial infections that include CRABC, but additional clinical data are needed to demonstrate efficacy.

Keyphrases

acinetobacter baumannii
multidrug resistant
drug resistant
pseudomonas aeruginosa
clinical trial
gram negative
electronic health record
cystic fibrosis
open label
phase ii
big data
randomized controlled trial
escherichia coli
double blind
phase iii