Adam B Shapiro

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 14

Top Venues

ACS infectious diseases

Antimicrobial agents and chemotherapy

Open forum infectious diseases

Journal of bacteriology

Entasis Therapeutics

Cornell University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Entasis Therapeutics

United States

Principle Scientist :: Biology

AstraZeneca R&D Boston

United States

Principle Scientist :: Infection Innovative Medicines

British Columbia Cancer Agency

Canada

Research Associate :: Victor Ling Laboratory

Ontario Cancer Institute

Canada

Postoctoral Research Fellow :: Victor Ling Laboratory

Education History

Cornell University

United States

PHD :: Section of Biochemistry, Molecular, and Cell Biology

Publications

Sarah M McLeod, Alita A Miller, Khurram Rana, David Altarac, Samir H Moussa, Adam B Shapiro
Clinical Outcomes for Patients With Monomicrobial vs Polymicrobial Acinetobacter baumannii-calcoaceticus Complex Infections Treated With Sulbactam-Durlobactam or Colistin: A Subset Analysis From a Phase 3 Clinical Trial. Open forum infectious diseases 11 (4) (2024)
Sarah M McLeod, Alita A Miller, Khurram Rana, David Altarac, Samir H Moussa, Adam B Shapiro
Clinical Outcomes for Patients With Monomicrobial vs Polymicrobial Acinetobacter baumannii-calcoaceticus Complex Infections Treated With Sulbactam-Durlobactam or Colistin: A Subset Analysis From a Phase 3 Clinical Trial. Open forum infectious diseases 11 (4) (2024)
Samir H Moussa, Adam B Shapiro, Sarah M McLeod, Ramkumar Iyer, Nicole M Carter, Yu-Kuo Tsai, L Kristopher Siu, Alita A Miller
Molecular drivers of resistance to sulbactam-durlobactam in contemporary clinical isolates of Acinetobacter baumannii . Antimicrobial agents and chemotherapy (2023)
Thomas F Durand-Reville, Alita A Miller, John P O'Donnell, Xiaoyun Wu, Mark A Sylvester, Satenig Guler, Ramkumar Iyer, Adam B Shapiro, Nicole M Carter, Camilo Velez-Vega, Samir H Moussa, Sarah M McLeod, April Chen, Angela M Tanudra, Jing Zhang, Janelle Comita-Prevoir, Jan A Romero, Hoan Huynh, Andrew D Ferguson, Peter S Horanyi, Stephen J Mayclin, Henry S Heine, George L Drusano, Jason E Cummings, Richard A Slayden, Rubén A Tommasi
Rational design of a new antibiotic class for drug-resistant infections. Nature 597 (7878) (2021)
Krisztina M Papp-Wallace, Adam B Shapiro, Scott A Becka, Elise T Zeiser, John J LiPuma, Douglas J Lane, Rekha G Panchal, John P Mueller, John P O'Donnell, Alita A Miller
In Vitro Antibacterial Activity and In Vivo Efficacy of Sulbactam-Durlobactam against Pathogenic Burkholderia Species. Antimicrobial agents and chemotherapy 65 (3) (2021)
Elizabeth T Montaño, Jason F Nideffer, Joseph Sugie, Eray Enustun, Adam B Shapiro, Hannah Tsunemoto, Alan I Derman, Kit Pogliano, Joe Pogliano
Bacterial Cytological Profiling Identifies Rhodanine-Containing PAINS Analogs as Specific Inhibitors of Escherichia coli Thymidylate Kinase In Vivo. Journal of bacteriology 203 (19) (2021)
Alita A Miller, Adam B Shapiro, Sarah M McLeod, Nicole M Carter, Samir H Moussa, Rubén A Tommasi, John P Mueller
In Vitro Characterization of ETX1317, a Broad-Spectrum β-Lactamase Inhibitor That Restores and Enhances β-Lactam Activity against Multi-Drug-Resistant Enterobacteriales, Including Carbapenem-Resistant Strains. ACS infectious diseases 6 (6) (2020)
Adam B Shapiro, Ning Gao
Interactions of the Diazabicyclooctane Serine β-Lactamase Inhibitor ETX1317 with Target Enzymes. ACS infectious diseases 7 (1) (2020)
Adam B Shapiro, Samir H Moussa, Nicole M Carter, Ning Gao, Alita A Miller
Ceftazidime-Avibactam Resistance Mutations V240G, D179Y, and D179Y/T243M in KPC-3 β-Lactamase Do Not Alter Cefpodoxime-ETX1317 Susceptibility. ACS infectious diseases 7 (1) (2020)
Thomas F Durand-Réville, Janelle Comita-Prevoir, Jing Zhang, Xiaoyun Wu, Tricia L May-Dracka, Jan Antoinette C Romero, Frank Wu, April Chen, Adam B Shapiro, Nicole M Carter, Sarah M McLeod, Robert A Giacobbe, Jeroen C Verheijen, Sushmita D Lahiri, Michael D Sacco, Yu Chen, John P O'Donnell, Alita A Miller, John P Mueller, Rubén A Tommasi
Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β-Lactamases. Journal of medicinal chemistry 63 (21) (2020)
Adam B Shapiro, Janelle Comita-Prevoir, Mark Sylvester
5-Carboxytetramethylrhodamine-Ampicillin Fluorescence Anisotropy-Based Assay of Escherichia coli Penicillin-Binding Protein 2 Transpeptidase Inhibition. ACS infectious diseases 5 (6) (2019)
Sarah M McLeod, Adam B Shapiro, Samir H Moussa, Michele Johnstone, Robert E McLaughlin, Boudewijn L M de Jonge, Alita A Miller
Frequency and Mechanism of Spontaneous Resistance to Sulbactam Combined with the Novel β-Lactamase Inhibitor ETX2514 in Clinical Isolates of Acinetobacter baumannii. Antimicrobial agents and chemotherapy 62 (2) (2018)
Adam B Shapiro, Ning Gao, Haris Jahić, Nicole M Carter, April Chen, Alita A Miller
Reversibility of Covalent, Broad-Spectrum Serine β-Lactamase Inhibition by the Diazabicyclooctenone ETX2514. ACS infectious diseases 3 (11) (2017)
Adam B Shapiro
Kinetics of Sulbactam Hydrolysis by β-Lactamases, and Kinetics of β-Lactamase Inhibition by Sulbactam. Antimicrobial agents and chemotherapy 61 (12) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Adam B Shapiro