The Staphylococcus aureus regulatory program in a human skin-like environment.
Flavia G CostaKrista B MillsHeidi A CrosbyAlexander R HorswillPublished in: mBio (2024)
upregulation of colonization and virulence factors using a newly developed medium that strives to replicate the human skin surface environment and demonstrates roles for adhesins clumping factor A (ClfA), serine-rich repeat glycoprotein adhesin (SraP), and the fibronectin binding proteins (Fnbps) in human corneocyte adherence.
Keyphrases
- staphylococcus aureus
- biofilm formation
- endothelial cells
- escherichia coli
- pseudomonas aeruginosa
- poor prognosis
- transcription factor
- induced pluripotent stem cells
- quality improvement
- methicillin resistant staphylococcus aureus
- cell proliferation
- pluripotent stem cells
- antimicrobial resistance
- type diabetes
- adipose tissue
- protein kinase