High expression levels of circulating microRNA-122 and microRNA-222 are associated with obesity in children with Mayan ethnicity.
Larissa Michelle González-ArceJulio César Lara-RiegosGerardo José Pérez-MendozaRodrigo Rubí-CastellanosMiguel Vega-MarcínGuillermo Valencia-PachecoJulio César Torres-RomeroLizbeth Josefina González-HerreraPublished in: American journal of human biology : the official journal of the Human Biology Council (2020)
The HELs of circulating miR-122 conferred a 3.85-fold increase in the risk for obesity, whereas the HELs of both miR-122 and miR-222 conferred a 3.11-fold increase in the risk for obesity, which were also associated with higher anthropometric or biochemical parameters, such as BMI, WHR, fat percentage, serum high-density lipid levels, TGs, and MI, in Mayan children.