Probiotics for the prevention of surgical necrotising enterocolitis: systematic review and meta-analysis.
Clare M ReesNigel J HallPaul FlemingSimon EatonPublished in: BMJ paediatrics open (2017)
Despite 35 RCTs on probiotic prevention of NEC, evidence for prevention of surgical NEC is not strong, partly due to poor reporting. In studies included in this meta-analysis, probiotic administration was associated with a reduction in NEC-related mortality.