Genome Sequence of the Human Opportunistic Fungus Arthrocladium fulminans (CBS 136243).
Leandro Ferreira MorenoNickolas Menezes da SilvaVinicius Almir WeissFlavia de Fátima CostaJuliana V BittencourtLuciano Medina MacedoRenata R GomesEmanuel Maltempi de SouzaVânia Aparecida VicenteBenjamin StielowGerrit Sybren de HoogPublished in: G3 (Bethesda, Md.) (2020)
The black yeast-like fungus Arthrocladium fulminans is known from strains that cause severe and eventually fatal disseminated infections in immunocompromised patients. Given the dramatic outcome of this clinical case, it is essential to understand the virulence potential of this species. The fungus is a member of the family Trichomeriaceae, at some phylogenetic distance from the Herpotrichiellaceae where most infectious fungi in the order Chaetothyriales are located. Main ecological preferences among Trichomeriaceae include colonization of exposed inert surfaces. Currently, black yeasts genomes that are available in public databases cover members of the families Herpotrichiellaceae and Cyphellophoraceae In the present report, we sequenced the genome of the first member and only clinical representative of the family Trichomeriaceae.
Keyphrases
- escherichia coli
- end stage renal disease
- endothelial cells
- ejection fraction
- biofilm formation
- chronic kidney disease
- newly diagnosed
- healthcare
- staphylococcus aureus
- pseudomonas aeruginosa
- human health
- prognostic factors
- climate change
- intensive care unit
- early onset
- risk assessment
- cross sectional
- cystic fibrosis
- dna methylation
- pluripotent stem cells
- gene expression
- artificial intelligence
- induced pluripotent stem cells