Longitudinal changes in resting-state functional connectivity as markers of vulnerability or resilience in first-degree relatives of patients with bipolar disorder.

Julian Macoveanu Lydia Fortea Hanne Lie Kjærstad Klara CoelloMaria Faurholt-JepsenPatrick MacDonald Fisher Gitte Moos Knudsen Joaquim Raduà Eduard Vieta Sophia Frangou Maj Vinberg Lars Vedel Kessing Kamilla Woznica Miskowiak

Published in: Psychological medicine (2024)

Our findings indicate the coexistence of both vulnerability-related abnormalities in resting-state connectivity, as well as adaptive changes possibly promoting resilience to psychopathology in individual at familial risk.

Keyphrases

resting state
climate change
functional connectivity
bipolar disorder
major depressive disorder
social support
early onset
cross sectional
multiple sclerosis
depressive symptoms
white matter