Cell-free DNA 5-hydroxymethylcytosine profiles of long non-coding RNA genes enable early detection and progression monitoring of human cancers.
Meng ZhouPing HouCongcong YanLu ChenKe LiYiran WangJingting ZhaoJianzhong SuJie SunPublished in: Clinical epigenetics (2021)
The present study will contribute to the ongoing effort to understand the transcriptional programs of lncRNA genes, as well as facilitate the development of novel invasive genomic tools for early cancer detection and surveillance.
Keyphrases
- long non coding rna
- poor prognosis
- public health
- genome wide
- endothelial cells
- bioinformatics analysis
- papillary thyroid
- genome wide identification
- gene expression
- transcription factor
- genome wide analysis
- induced pluripotent stem cells
- dna methylation
- pluripotent stem cells
- squamous cell carcinoma
- childhood cancer
- loop mediated isothermal amplification
- young adults
- long noncoding rna
- real time pcr
- sensitive detection