De Novo Design of Integrin α5β1 Modulating Proteins for Regenerative Medicine.
Xinru WangJordi Guillem-MartiSaurav KumarDavid S LeeDaniel Cabrerizo-AguadoRachel WertherKevin Alexander Estrada AlamoYan Ting ZhaoAdam NguyenIrina KopyevaBuwei HuangJing LiYuxin HaoXinting LiAritza Brizuela-VelascoAnalisa MurrayStacey GerbenAnalisa N MurrayCole A DeForestTimothy A SpringerHannele Ruohola-BakerJonathan A CooperMelody G CampbellJose Maria ManeroMaria-Pau GinebraJulien S BakerPublished in: bioRxiv : the preprint server for biology (2024)
A de novo-designed fibronectin substitute, NeoNectin, is specific for integrin α5β1 and can be incorporated into biomaterials for regenerative medicine.