Western Dietary Pattern Is Associated With Severe Coronary Artery Disease.
Evaggelos OikonomouTheodora PsaltopoulouGeorgios GeorgiopoulosGerasimos SiasosEleni KokkouAlexios AntonopoulosGeorgia VogiatziSotirios TsalamandrisVassiliki GennimataAggelos PapanikolaouDimitris TousoulisPublished in: Angiology (2017)
The independent predictive value of an unhealthy diet on the severity of coronary artery disease (CAD) requires further investigation. We assessed the impact of dietary pattern on CAD severity. In this cohort study, we included 188 symptomatic stable patients with CAD. Patients were categorized as having severe CAD or nonsevere CAD by coronary angiography. Among several demographics and clinical characteristics, all patients were tested using a semiquantitative food frequency questionnaire. Concerning baseline demographic characteristics, there was no difference between patients with severe CAD and nonsevere CAD. Principal component analysis revealed 8 distinct dietary patterns. The first component Western dietary pattern (increased intake of fat, red meat, and carbohydrates and minimal consumption of fruits and green leafy vegetables) was predictive of severe CAD (area under the curve: 0.73, 95% confidence intervals: 0.64-0.83, P < .001). In conclusion, an unhealthy Western type of diet is associated with the severity of coronary artery lesions in patients with stable CAD. These findings highlight the role of dietary patterns when estimating cardiovascular risk for the management of patients with CAD.
Keyphrases
- coronary artery disease
- percutaneous coronary intervention
- coronary artery bypass grafting
- cardiovascular events
- end stage renal disease
- coronary artery
- newly diagnosed
- ejection fraction
- early onset
- south africa
- peritoneal dialysis
- prognostic factors
- weight loss
- drug induced
- type diabetes
- cardiovascular disease
- patient reported outcomes
- heart failure
- pulmonary artery
- single cell
- cross sectional
- weight gain
- fatty acid
- pulmonary hypertension
- acute coronary syndrome