Effects of CO2 limitation on the metabolism of Pseudoclostridium thermosuccinogenes.

Jeroen Girwar KoendjbiharieWilbert Berend PostMartí Munar PalmerRichard van Kranenburg

Published in: BMC microbiology (2020)

The results hinted at a decreased NAD+/NADH ratio, which could ultimately be responsible for the stress observed during CO2 limitation. Clear overexpression of an alcohol dehydrogenase (adhE) was observed, which may explain the increased ethanol production, while no changes were seen for PFL and PFOR expression that could explain the anticipated switch based on the fermentation results.

Keyphrases

poor prognosis
cell proliferation
transcription factor
saccharomyces cerevisiae
binding protein
alcohol consumption
lactic acid
heat stress