Meta-Analysis of the Prognostic and Predictive Role of the CpG Island Methylator Phenotype in Colorectal Cancer.
Jing WangZhujun DengXiaoqiang LangJuan JiangKang XieSifen LuQiongxia HuYuwei HuoXinru XiongNiu ZhuWengeng ZhangPublished in: Disease markers (2022)
CIMP-H is associated with a significantly poor prognosis in CRC patients, especially those with stage III-IV and pMMR tumors. However, the predictive value of CIMP needs to be confirmed by more prospective randomized studies.
Keyphrases
- poor prognosis
- systematic review
- end stage renal disease
- long non coding rna
- ejection fraction
- newly diagnosed
- chronic kidney disease
- case control
- dna methylation
- peritoneal dialysis
- double blind
- prognostic factors
- open label
- meta analyses
- gene expression
- clinical trial
- phase iii
- randomized controlled trial
- placebo controlled