Single-cell Expression Atlas Reveals Cell Heterogeneity in the Creeping Fat of Crohn's Disease.

Weigang ShuYongheng WangChuanding LiLei ZhangDeji ZhuomaPengyu YangGuorong YanChunqiu ChenYongbing BaPeng DuXiaolei Wang

Published in: Inflammatory bowel diseases (2023)

Our results uncover the cellular heterogeneity in the MAT of CD and the role of these various cellular compositions in CrF development. This comprehensive understanding of CrF provides future directions for in-depth research on and potential targets for MAT-based treatment.

Keyphrases

single cell
rna seq
high throughput
poor prognosis
adipose tissue
optical coherence tomography
fatty acid
binding protein
current status
combination therapy
risk assessment
cell therapy
bone marrow
replacement therapy