Green Synthesis of Low-Glycemic Amylose-Lipid Nanocomposites by High-Speed Homogenization and Formulation into Hydrogel.
Nasir Mehmood KhanMisbah UddinEbenezer Ola FaladeFarman Ali KhanJian WangMuhammad ShafiqueReem M AlnemariMaram H AbduljabbarShujaat AhmadPublished in: Molecules (Basel, Switzerland) (2023)
In this research, we focused on the production of amylose-lipid nanocomposite material (ALN) through a green synthesis technique utilizing high-speed homogenization. Our aim was to investigate this novel material's distinctive physicochemical features and its potential applications as a low-glycemic gelling and functional food ingredient. The study begins with the formulation of the amylose-lipid nanomaterial from starch and fatty acid complexes, including stearic, palmitic, and lauric acids. Structural analysis reveals the presence of ester carbonyl functionalities, solid matrix structures, partial crystallinities, and remarkable thermal stability within the ALN. Notably, the ALN exhibits a significantly low glycemic index (GI, 40%) and elevated resistance starch (RS) values. The research extends to the formulation of ALN into nanocomposite hydrogels, enabling the evaluation of its anthocyanin absorption capacity. This analysis provides valuable insights into the rheological properties and viscoelastic behavior of the resulting hydrogels. Furthermore, the study investigates anthocyanin encapsulation and retention by ALN-based hydrogels, with a particular focus on the influence of pH and physical cross-link networks on the uptake capacity presenting stearic-acid (SA) hydrogel with the best absorption capacity. In conclusion, the green-synthesized (ALN) shows remarkable functional and structural properties. The produced ALN-based hydrogels are promising materials for a variety of applications, such as medicine administration, food packaging, and other industrial purposes.
Keyphrases
- drug delivery
- high speed
- hyaluronic acid
- atomic force microscopy
- fatty acid
- tissue engineering
- type diabetes
- wound healing
- drug release
- reduced graphene oxide
- extracellular matrix
- high resolution
- physical activity
- carbon nanotubes
- climate change
- risk assessment
- single molecule
- case report
- gold nanoparticles
- highly efficient
- simultaneous determination