Extracapsular extension, pathologic node status, and adjuvant treatment in primary surgery patients with human papillomavirus-mediated oropharyngeal cancer: National hospital-based retrospective cohort analysis.
Andrew T DayAlex M YangPriscilla TanamalJames-Michael BlackwellEllen WangBaran D SumerJustin A BishopRandall S HughesSaad A KhanDavid J SherPublished in: Head & neck (2021)
Although pathologic ECE negatively predicts for survival in patients with HPV+ OPC, our analyses support expansion of postoperative de-intensification clinical trial eligibility criteria in patients with ECE-positive disease.
Keyphrases
- clinical trial
- neoadjuvant chemotherapy
- minimally invasive
- papillary thyroid
- locally advanced
- early stage
- lymph node
- patients undergoing
- coronary artery bypass
- quality improvement
- squamous cell
- study protocol
- cross sectional
- randomized controlled trial
- open label
- surgical site infection
- free survival
- rectal cancer
- lymph node metastasis
- double blind
- childhood cancer
- coronary artery disease
- percutaneous coronary intervention
- smoking cessation
- data analysis