The pathophysiology of diabetic gastroparesis (DGP), a common complication in diabetic patients, is not fully known. Its development has been linked to several causes, including hyperglycaemia, vagal nerve dysfunction, aberrant Cajal's interstitial cell network (ICC), lack of nerve nitric oxide synthase (nNOS) expression in the intermuscular plexus, and hormonal alterations in the gastrointestinal tract. Glucose management, diet control, gastric stimulants, anti-emetic medications, Helicobacter pylori eradication, stomach electrical stimulation, and surgery are the main current treatments. These methods, however, could have unfavourable consequences. By examining recent studies and literature reviews, we outline the state of the study on diabetic gastroparesis in this paper.
Keyphrases
- helicobacter pylori
- nitric oxide synthase
- helicobacter pylori infection
- type diabetes
- nitric oxide
- wound healing
- poor prognosis
- systematic review
- minimally invasive
- physical activity
- single cell
- coronary artery bypass
- oxidative stress
- peripheral nerve
- stem cells
- cell therapy
- coronary artery disease
- blood glucose
- randomized controlled trial
- polycystic ovary syndrome
- surgical site infection
- bone marrow
- atrial fibrillation