Role of Cachexia and Fragility in the Patient Candidate for Cardiac Surgery.
Calogera PisanoDaniele PolisanoCarmela Rita BalistreriClaudia AltieriPaolo NardiFabio BertoldoDaniele TrombettiLaura AstaMaria Sabrina FerranteDario BuioniCalogero FotiGiovanni RuvoloPublished in: Nutrients (2021)
Frailty is the major expression of accelerated aging and describes a decreased resistance to stressors, and consequently an increased vulnerability to additional diseases in elderly people. The vascular aging related to frail phenotype reflects the high susceptibility for cardiovascular diseases and negative postoperative outcomes after cardiac surgery. Sarcopenia can be considered a biological substrate of physical frailty. Malnutrition and physical inactivity play a key role in the pathogenesis of sarcopenia. We searched on Medline (PubMed) and Scopus for relevant literature published over the last 10 years and analyzed the strong correlation between frailty, sarcopenia and cardiovascular diseases in elderly patient. In our opinion, a right food intake and moderate intensity resistance exercise are mandatory in order to better prepare patients undergoing cardiac operation.
Keyphrases
- community dwelling
- patients undergoing
- cardiovascular disease
- high intensity
- physical activity
- cardiac surgery
- case report
- mental health
- systematic review
- poor prognosis
- climate change
- skeletal muscle
- left ventricular
- resistance training
- heart failure
- type diabetes
- cardiovascular risk factors
- randomized controlled trial
- long non coding rna
- atrial fibrillation
- metabolic syndrome
- adipose tissue
- body composition
- cardiovascular events
- insulin resistance
- binding protein
- meta analyses