Effectiveness of non-pharmacological COPD management on health-related quality of life - a systematic review.
Michael HindelangFlorian KirschReiner LeidlPublished in: Expert review of pharmacoeconomics & outcomes research (2020)
Introduction: Chronic obstructive pulmonary disease (COPD) is the third leading cause of mortality worldwide. The chronic progressive disease is accompanied by a high loss of health-related quality of life (HRQoL). The available drugs usually only have symptomatic effects; therefore, non-pharmacological therapies are essential too.Areas covered: This systematic review examines non-pharmacological interventions consisting of pulmonary rehabilitation, physical activity, and training versus usual care or no intervention in COPD using at least one of the following HRQoL measuring instruments: St. George's Respiratory Questionnaire, Clinical COPD Questionnaire, COPD Assessment Test, and EuroQol-5D. Of 1532 identified records from CENTRAL, MEDLINE, and EMBASE, 15 randomized controlled trials met the inclusion criteria. Pulmonary rehabilitation programs were investigated in nine studies, education and counseling-based training programs in three studies, and breathing exercises in three studies. Ten studies were found that investigated non-pharmacological treatment programs that led to a significant and clinically relevant improvement in HRQoL compared with usual care or no treatment.Expert opinion: Non-pharmacological interventions consisting of pulmonary rehabilitation, education and counseling-based training programs, and breathing exercises can improve the HRQoL of COPD patients.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- systematic review
- physical activity
- healthcare
- randomized controlled trial
- public health
- pulmonary hypertension
- quality improvement
- end stage renal disease
- palliative care
- case control
- multiple sclerosis
- cystic fibrosis
- chronic kidney disease
- virtual reality
- cardiovascular events
- newly diagnosed
- cross sectional
- air pollution
- clinical trial
- patient reported
- risk factors
- depressive symptoms
- hepatitis c virus
- pain management
- patient reported outcomes
- smoking cessation
- hiv testing
- replacement therapy
- affordable care act
- human immunodeficiency virus
- mass spectrometry
- double blind