Screening Failure in a Large Clinical Trial Centre for Inflammatory Bowel Diseases: Rates, Causes, and Outcomes.
An OuttierLiese GijbelsMaja NomanBram VerstocktJoão SabinoSéverine VermeireMarc FerrantePublished in: Inflammatory bowel diseases (2022)
A significant proportion of IBD patients consenting to clinical trials fail their screening. Main causes of SF are ineligible disease activity and abnormal finding on microbiology. Approximately one-fourth of SFs could have been avoided by prescreening that was more thorough.
Keyphrases
- clinical trial
- disease activity
- rheumatoid arthritis
- systemic lupus erythematosus
- end stage renal disease
- rheumatoid arthritis patients
- ejection fraction
- chronic kidney disease
- ankylosing spondylitis
- newly diagnosed
- phase ii
- peritoneal dialysis
- open label
- prognostic factors
- study protocol
- randomized controlled trial
- type diabetes
- double blind
- metabolic syndrome
- phase iii
- patient reported
- ulcerative colitis