Ten-Year Follow-up of Internal Neurofibroma Growth Behavior in Adult Patients With Neurofibromatosis Type 1 Using Whole-Body MRI.
K Ina LyVanessa L MerkerWenli CaiMiriam A BredellaAlona MuzikanskyRaquel D ThalheimerJennifer Liwei DaChristina C OrrHamilton P HerrMary E MorrisConnie Y ChangGordon J HarrisScott R PlotkinJustin T JordanPublished in: Neurology (2022)
Internal neurofibroma growth behavior in older adults differs fundamentally from that in children and young adults, with most tumors, including DNL, demonstrating spontaneous shrinkage. Better growth models are needed to understand factors that influence tumor growth. These results will inform clinical trial design for internal neurofibromas.