Title: β Cell microRNAs Function as Molecular Hubs of Type 1 Diabetes Pathogenesis and as Biomarkers of Diabetes Risk.

Farooq SyedPreethi KrishnanGarrick ChangSarah R LanglaisSumon HatiKentaro YamadaAnh K LamSayali TalwareXiaowen LiuRajesh SardarJing LiuRaghavendra G Mirmira Carmella Evans-Molina

Published in: bioRxiv : the preprint server for biology (2023)

miRNA expression patterns in human pancreatic islets and EVs change under inflammatory conditions and can be leveraged to inform biomarkers strategies for T1D.

Keyphrases

endothelial cells
poor prognosis
type diabetes
cardiovascular disease
single cell
cell therapy
oxidative stress
induced pluripotent stem cells
glycemic control
pluripotent stem cells
binding protein
long non coding rna
insulin resistance