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Eye on genome editing.

Samuel W DuKrzysztof Palczewski
Published in: The Journal of experimental medicine (2023)
CRISPR/Cas9 genome editing techniques have the potential to treat previously untreatable inherited genetic disorders of vision by correcting mutations that cause these afflictions. Using a prime editor, Qin et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20220776) restored visual functions in a mouse model (rd10) of retinitis pigmentosa.
Keyphrases
  • genome editing
  • crispr cas
  • mouse model
  • genome wide
  • human health
  • risk assessment
  • dna methylation
  • climate change