NOD-like receptor pyrin domain-containing-3 (NLRP3) regulates inflammation-induced pro-labor mediators in human myometrial cells.

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2018)

NLRP3 is increased with labor in myometrial, and knockdown of NLRP3 is associated with an attenuation of inflammation-induced expression of pro-inflammatory and pro-labor mediators in human myometrium.

Keyphrases

endothelial cells
high glucose
oxidative stress
diabetic rats
induced apoptosis
poor prognosis
induced pluripotent stem cells
pluripotent stem cells
anti inflammatory
nlrp inflammasome
drug induced
binding protein
signaling pathway
long non coding rna