Role of the mitochondrial citrate-oxoglutarate carrier in lipid accumulation in the oleaginous fungus Mortierella alpina.

Fengzhu LingXin TangHao ZhangYong Q ChenJianxin ZhaoHaiqin ChenWei Chen

Published in: Biotechnology letters (2021)

Overexpression of MaYHM resulted in more efflux of citrate from mitochondria to the cytoplasm and enhanced lipid accumulation. These findings provide new perspectives for the improvement of industrial lipid production in M. alpina.

Keyphrases

oxidative stress
wastewater treatment
heavy metals
cell proliferation
cell death
fatty acid
transcription factor
endoplasmic reticulum
reactive oxygen species