Intra- and interindividual attack frequency variability of chronic cluster headache.

Roemer B BrandtWim MullenersLeopoldine A WilbrinkPaul BrandtErik W van ZwetFrank Jpm HuygenMichel D FerrariRolf Fronczeknull null

Published in: Cephalalgia : an international journal of headache (2023)

Weekly retrospective attack frequency recording is as good as instantaneous recording and more convenient. Attack frequency is highest in spring. Participants with ≥3 daily attacks show less attack frequency variability than those with <3 daily attacks. An optimal balance between 90% accuracy and feasibility is achieved at a baseline period of seven weeks.The ICON trial is registered in ClinicalTrials.gov under number NCT01151631.

Keyphrases

physical activity
clinical trial
study protocol
cross sectional
randomized controlled trial
phase iii
drug induced
preterm birth