Single-cell image analysis reveals over-expression of organic anion transporting polypeptides (OATPs) in human glioblastoma tissue.
Elizabeth CooperZoe WoolfMolly E V SwansonJason CorreiaPatrick SchwederEdward W MeePeter HeppnerClinton P TurnerRichard L M FaullEmma L ScotterWilliam A DennyPeter J ChoiMichael DragunowJiney JoseThomas In Hyeup ParkPublished in: Neuro-oncology advances (2022)
Here, we demonstrate, for the first time, the protein expression of four OATPs in human GBM tissue, including upregulation within the tumor microenvironment by myeloid cells and tumor vasculature, and isoform-specific upregulation within hypoxic niches.