Genomic DNA methylation distinguishes subtypes of human focal cortical dysplasia.
Katja KobowMark ZiemannHarikrishnan KaipananickalIshant KhuranaAngelika MühlebnerMartha FeuchtJohannes A HainfellnerThomas CzechEleonora AronicaTom PieperHans HolthausenManfred KudernatschHajo M HamerBurkhard S KasperKarl RösslerValerio ContiRenzo GuerriniRoland CorasIngmar BlümckeAssam El-OstaAntony KaspiPublished in: Epilepsia (2019)
Our studies extend the evidence for disease-specific methylation signatures toward focal epilepsies in favor of an integrated clinicopathologic and molecular classification system of FCD subtypes incorporating genomic methylation.