orsai, the Drosophila homolog of human ETFRF1, links lipid catabolism to growth control.
Magdalena Fernandez-AcostaJuan Ignacio RomeroGuillermo BernabóGiovanna M Velázquez-CamposNerina GonzalezM Lucía MaresSantiago WerbajhL Amaranta Avendaño-VázquezGerald N RechbergerRonald P KühnleinCristina Marino-BusljeRafael CanteraCarolina RezavalMaría Fernanda CerianiPublished in: BMC biology (2022)
These findings suggest that Osi may act in concert with the ETF complex to coordinate lipid homeostasis in the fat body in response to stage-specific demands, supporting cellular functions that in turn result in an adaptive behavioral response.