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The landscape of human tissue and cell type specific expression and co-regulation of senescence genes.

Peng XuMinghui WangWon-Min SongQian WangGuo-Cheng YuanPeter H SudmantHabil ZareZhidong TuMiranda E OrrBin Zhang
Published in: Molecular neurodegeneration (2022)
This study systematically revealed the co-regulated organizations and cell type specificity of SnGs in major human tissues, which can serve as a blueprint for future studies to map senescent cells and their cellular interactions in human tissues.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • poor prognosis
  • induced apoptosis
  • single cell
  • genome wide
  • transcription factor
  • dna methylation
  • cell death
  • cell cycle arrest
  • current status