plantMASST - Community-driven chemotaxonomic digitization of plants.
Paulo Wender Portal GomesHelena M RussoRobin SchmidSimone ZuffaTito DamianiLuis-Manuel Quiros-GuerreroAndrés Mauricio Caraballo-RodriguezHaoqi Nina ZhaoHeejung YangShipei XingVincent Charron-LamoureuxDesnor N ChigumbaBrian E SedioJonathan A MyersPierre-Marie AllardThomas V HarwoodGiselle Tamayo-CastilloKyo-Bin KangEmmanuel DefossezHector Henrique Ferreira KoolenMilton Nascimento da SilvaConsuelo Yumiko Yoshioka E SilvaSergio RasmannTom W N WalkerGaëtan GlauserJosé Miguel Chaves-FallasBruno DavidHyun Woo KimKyu Hyeong LeeMyeong Ji KimWon Jun ChoiYoung-Sam KeumEmilly J S P de LimaLívia Soman de Medeiros MedeirosGiovana A BataglionEmmanoel V CostaFelipe Moura Araújo da SilvaAlice Rhelly V CarvalhoJosé Diogo E ReisSônia PamplonaEunah JeongKyungha LeeGeum Jin KimYun-Seo KilJoo-Won NamHyukjae ChoiYoo Kyong HanSi Young ParkKi Yong LeeChangling HuYilun DongShengmin SangColin R MorrisonRicardo Moreira BorgesAndrew Magno TeixeiraSeo Yoon LeeBum Soo LeeSe Yun JeongKi Hyun KimAdriano RutzArnaud GaudryEdouard BruelhartIris F KappersRumyana KarlovaMara MeisenburgRoland BerdaguerJ Sebastián TelloDavid HendersonLeslie CayolaS Joseph WrightDavid N AllenKristina J Anderson-TeixeiraJennifer L BaltzerJames A LutzSean M McMahonGeoffrey G ParkerJohn D ParkerTrent R NorthenBenjamin P BowenTomáš PluskalJustin Johan Jozias van der HooftJeremy J CarverNuno BandeiraBenjamin S PullmanJean-Luc WolfenderRoland D KerstenMingxun WangPieter C DorresteinPublished in: bioRxiv : the preprint server for biology (2024)
Understanding the distribution of hundreds of thousands of plant metabolites across the plant kingdom presents a challenge. To address this, we curated publicly available LC-MS/MS data from 19,075 plant extracts and developed the plantMASST reference database encompassing 246 botanical families, 1,469 genera, and 2,793 species. This taxonomically focused database facilitates the exploration of plant-derived molecules using tandem mass spectrometry (MS/MS) spectra. This tool will aid in drug discovery, biosynthesis, (chemo)taxonomy, and the evolutionary ecology of herbivore interactions.
Keyphrases
- ms ms
- tandem mass spectrometry
- drug discovery
- cell wall
- ultra high performance liquid chromatography
- high performance liquid chromatography
- liquid chromatography
- healthcare
- simultaneous determination
- mental health
- photodynamic therapy
- adverse drug
- electronic health record
- squamous cell carcinoma
- liquid chromatography tandem mass spectrometry
- mass spectrometry
- radiation therapy
- density functional theory
- combination therapy
- cancer therapy
- genetic diversity