Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex.
Chengyu DengSean WhalenMarilyn SteyertRyan ZiffraPawel F PrzytyckiFumitaka InoueDaniela A PereiraDavide CapautoScott NortonFlora M VaccarinoAlex Aaron PollenTomasz J NowakowskiNadav AhituvKatherine S PollardPublished in: bioRxiv : the preprint server for biology (2023)
We identify 46,802 enhancers and 164 psychiatric disorder variants with regulatory effects in the developing cortex and organoids.