Non-alcoholic fatty liver disease and risk of new-onset heart failure: an updated meta-analysis of about 11 million individuals.
Alessandro MantovaniGraziana PetraccaAlessandro CsermelyGiorgia BeatriceStefano BonapaceAndrea RossiHerbert TilgChristopher D ByrneGiovanni TargherPublished in: Gut (2022)
NAFLD is associated with a 1.5-fold higher long-term risk of new-onset HF, regardless of the presence of diabetes, hypertension and other common cardiovascular risk factors. However, the observational design of the studies does not allow for proving causality.
Keyphrases
- cardiovascular risk factors
- cardiovascular disease
- heart failure
- case control
- systematic review
- blood pressure
- metabolic syndrome
- acute heart failure
- type diabetes
- meta analyses
- glycemic control
- left ventricular
- cross sectional
- liver fibrosis
- atrial fibrillation
- randomized controlled trial
- emergency department
- skeletal muscle