Transcribed ultraconserved region (T-UCR) uc.261 expression is closely correlated with disease activity and intestinal permeability in Crohn's disease.

Xiao-Xian QianChen-Wen CaiHan-Yang LiLi-Jie LaiDong-Juan SongYu-Qi QiaoJun ShenZhi-Hua Ran

Published in: Therapeutic advances in gastroenterology (2019)

Uc.261 expression was closely correlated with disease activity and intestinal permeability in CD. Anti-TNF-α treatment may play its role through suppressing uc.261 expression in colitis mice.

Keyphrases

disease activity
rheumatoid arthritis
systemic lupus erythematosus
poor prognosis
rheumatoid arthritis patients
ankylosing spondylitis
juvenile idiopathic arthritis
binding protein
endothelial cells
type diabetes
metabolic syndrome
combination therapy