The Impact of Ketamine for Treatment of Post-Traumatic Stress Disorder: A Systematic Review With Meta-Analyses.
Dakota J SicignanoRyan KurschnerNissen WeismanAva SedenskyAdrian V HernandezC Michael WhitePublished in: The Annals of pharmacotherapy (2023)
Ketamine modestly reduced PTSD and depression scores as early as 1 day of therapy, but the longevity of effect needs to be determined. Given similar magnitude of benefit with SSRIs and venlafaxine, ketamine would not supplant these traditional options for chronic use.