Combination of enamel matrix derivative and hyaluronic acid inhibits lipopolysaccharide-induced inflammatory response on human epithelial and bone cells.
Liza L RamenzoniLaura AnnasohnRichard J MironThomas AttinPatrick R SchmidlinPublished in: Clinical oral investigations (2021)
The use of EMD in conjunction with HA resulted in a reduction of inflammation and improvement of tissue healing at wound sites. Both biomaterials combined may potentially improve the effectiveness of bone regeneration in periodontal bone defects, pointing to the potential clinical relevance of both materials in regenerative periodontal surgery.
Keyphrases
- bone regeneration
- lipopolysaccharide induced
- inflammatory response
- hyaluronic acid
- induced apoptosis
- stem cells
- lps induced
- endothelial cells
- oxidative stress
- toll like receptor
- minimally invasive
- randomized controlled trial
- mesenchymal stem cells
- cell cycle arrest
- systematic review
- surgical site infection
- coronary artery bypass
- cell therapy
- pluripotent stem cells
- immune response
- induced pluripotent stem cells
- tissue engineering
- signaling pathway
- cell death
- coronary artery disease
- risk assessment
- wound healing
- acute coronary syndrome
- postmenopausal women