Longitudinal profiling of the gut microbiome in patients with psoriatic arthritis and ankylosing spondylitis: a multicentre, prospective, observational study.
Jesus Miguens BlancoFederica BorgheseNeil McHughPeter KelleherRaj SenguptaJulian R MarchesiSonya AbrahamPublished in: BMC rheumatology (2020)
The aim of this trial is to characterise the microbiome of psoriatic arthritis patients and to compare it with microbiome of healthy volunteers and of patient with ankylosing spondylitis in order to define if different rheumatologic conditions are associated with characteristic microbiome profiles. Investigating the role of the microbiome in the development of psoriatic arthritis could deepen our understanding of the pathogenesis of the disease and potentially open the way to new therapies.
Keyphrases
- ankylosing spondylitis
- disease activity
- rheumatoid arthritis
- end stage renal disease
- study protocol
- clinical trial
- ejection fraction
- newly diagnosed
- chronic kidney disease
- systemic lupus erythematosus
- cross sectional
- minimally invasive
- randomized controlled trial
- single cell
- double blind
- patient reported
- placebo controlled