The clinical efficacy and safety of granulocyte and monocyte adsorptive apheresis in patients with Crohn's disease: A multicenter retrospective pilot study.

Nobuhiro UenoSeisuke SaitoMasahiro SatoYuya SugiyamaYu KobayashiYuki MurakamiKohjiro SugimuraTakahiro SasakiAki SakataniKeitaro TakahashiKazuyuki TanakaShinya SerikawaKatsuyoshi AndoShin KashimaMomotaro MutoYuhei InabaKentaro MoriichiHiroki TanabeToshikatsu OkumuraMikihiro Fujiya

Published in: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy (2024)

GMA may exhibit effectiveness even in cases with refractory CD. Moreover, it represents a potential novel therapeutic option for refractory CD with loss of response to biologics.

Keyphrases

cross sectional
peripheral blood
randomized controlled trial
systematic review
dendritic cells
endothelial cells
clinical trial
recombinant human