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Lipidomics Analysis Deepen Understanding the Molecular Mechanisms in a Gouty Model Induced by Combination of MSU Crystals Injection and High-Fat Diet Feeding and the Intervention Mechanisms of Allopurinol.

Dianming LiWeiman ShiChangfeng HuChengping WenLin HuangQiao Wang
Published in: Journal of inflammation research (2024)
Our results indicated that various aberrant lipid metabolisms were present in the established gouty model, and allopurinol treatment could relief this aberrant metabolism of lipids to some degree.
Keyphrases
  • high fat diet
  • insulin resistance
  • adipose tissue
  • randomized controlled trial
  • fatty acid
  • type diabetes
  • room temperature
  • combination therapy
  • replacement therapy