Circulating Fatty Acids and Genetic Predisposition to Type 2 Diabetes: Gene-Nutrient Interaction Analysis.

Pan ZhuangXiaohui LiuYin LiHaoyu LiLange ZhangXuzhi WanYuqi WuYu ZhangJingjing Jiao

Published in: Diabetes care (2022)

Plasma concentrations of SFA and MUFA were associated with a higher T2D risk, whereas plasma PUFA and n-6 and n-3 PUFA were related to a lower risk. Circulating MUFA and n-3 PUFA had significant interactions with genetic predisposition to T2D and FA-associated variants.

Keyphrases

copy number
type diabetes
genome wide
fatty acid
gene expression
metabolic syndrome
adipose tissue
transcription factor