The effects of metformin, pioglitazone, exenatide and exercise on fatty liver in obese diabetic rats: the role of IRS-1 and SOCS-3 molecules.

Kemal Ozan LuleErsin AkarsuZeynel Abidin SayinerNezihe Otay LuleSibel Oguzkan BalciCan DemirelZehra BozdagMurat KorkmazIbrahim Yilmaz

Published in: Inflammopharmacology (2022)

Exercise and exenatide treatments seemed to be the prominent treatment methods by showing a statistically significant effect in decreasing the degree of steatosis, decreasing the Socs3 expression level and increasing the Irs-1 expression level.

Keyphrases

diabetic rats
poor prognosis
high intensity
oxidative stress
physical activity
adipose tissue
metabolic syndrome
type diabetes
insulin resistance
resistance training
binding protein
high fat diet
weight loss
skeletal muscle
fatty acid
replacement therapy