Implications of Cardiopulmonary Risk for the Management of COPD: A Narrative Review.
Dave SinghMeilan K HanNathaniel Mark HawkinsJohn R HurstJanwillem W H KocksNeil SkolnikDaiana StolzJad El KhouryChris P GalePublished in: Advances in therapy (2024)
Chronic obstructive pulmonary disease (COPD) constitutes a major global health burden and is the third leading cause of death worldwide. A high proportion of patients with COPD have cardiovascular disease, but there is also evidence that COPD is a risk factor for adverse outcomes in cardiovascular disease. Patients with COPD frequently die of respiratory and cardiovascular causes, yet the identification and management of cardiopulmonary risk remain suboptimal owing to limited awareness and clinical intervention. Acute exacerbations punctuate the progression of COPD in many patients, reducing lung function and increasing the risk of subsequent exacerbations and cardiovascular events that may lead to early death. This narrative review defines and summarises the principles of COPD-associated cardiopulmonary risk, and examines respiratory interventions currently available to modify this risk, as well as providing expert opinion on future approaches to addressing cardiopulmonary risk.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- cardiovascular disease
- cystic fibrosis
- cardiovascular events
- air pollution
- randomized controlled trial
- type diabetes
- end stage renal disease
- global health
- coronary artery disease
- chronic kidney disease
- public health
- newly diagnosed
- peritoneal dialysis
- hepatitis b virus
- extracorporeal membrane oxygenation
- patient reported