[Modern approaches to the diagnostics and treatment of the consequences of traumatic brain injury in children and adolescents].
S A NemkovaPublished in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2022)
The article is devoted to an important problem of modern pediatric neurology and rehabilitation, - the issues of diagnosis and comprehensive restorative treatment of the consequences of traumatic brain injury (TBI) in children and adolescents. It is known that TBI is characterized by a high frequency of disability, while asthenic, vegetative, cognitive, emotional, motor and postural disorders are leading in the clinical picture. It is shown that the factors influencing the severity of the consequences of TBI in children are not only the severity of the injury itself, but also the age at which the injury occurred, as well as the localization of the lesion. The article describes modern methods of complex diagnosis and rehabilitation of the consequences of TBI in children, as well as pathogenetically justified approaches to drug therapy, while showing the high effectiveness of the drug choline alfoscerate (Cereton) in restoring cognitive functions and improving the clinical condition in children with the consequences of TBI, according to the results of a double-blind placebo-controlled multicenter randomized trial.
Keyphrases
- traumatic brain injury
- high frequency
- severe traumatic brain injury
- young adults
- randomized controlled trial
- transcranial magnetic stimulation
- systematic review
- double blind
- multiple sclerosis
- placebo controlled
- mild traumatic brain injury
- emergency department
- squamous cell carcinoma
- study protocol
- drug induced
- bone marrow
- cell therapy
- phase ii study
- open label
- smoking cessation