Anatomical structures, cell types and biomarkers of the Human Reference Atlas.
Katy BörnerSarah A TeichmannEllen M QuardokusJames C GeeKristen BrowneDavid Osumi-SutherlandBruce W HerrAndreas BueckleHrishikesh PaulMuzlifah A HaniffaLaura JardineAmy BernardSong-Lin DingJeremy A MillerShin LinMarc K HalushkaAvinash BoppanaTeri A LongacreJohn HickeyYiing LinM Todd ValeriusYongqun Oliver HeGloria PryhuberXin SunMarda JorgensenAndrea J RadtkeClive WasserfallFiona GintyJonhan HoJoel SunshineRebecca T BeuschelMaigan BruskoSujin LeeRajeev MalhotraSanjay JainGriffin WeberPublished in: Nature cell biology (2021)
The Human Reference Atlas (HRA) aims to map all of the cells of the human body to advance biomedical research and clinical practice. This Perspective presents collaborative work by members of 16 international consortia on two essential and interlinked parts of the HRA: (1) three-dimensional representations of anatomy that are linked to (2) tables that name and interlink major anatomical structures, cell types, plus biomarkers (ASCT+B). We discuss four examples that demonstrate the practical utility of the HRA.