Effects of the Rho-Kinase Inhibitor Y-27632 on Extraocular Muscle Surgery in Rabbits.
Ji-Sun MoonHyun Kyung KimSun Young ShinPublished in: Journal of ophthalmology (2017)
F4/80 antibody expression was significantly different in the Rho-kinase inhibitor-injected group at both postoperative day 3 and week 4 (p = 0.038, 0.031). However, Ki-67 and CD11β+ were not different the between two groups. The difference in the SRM/conjunctiva adhesion score between the two groups was also significant (p = 0.034). Conclusion. Intraoperative subconjunctival injection of the Rho-kinase inhibitor may be effective for adjunctive management of inflammation and fibrosis in rabbit eyes following extraocular muscle surgery.
Keyphrases
- minimally invasive
- coronary artery bypass
- protein kinase
- skeletal muscle
- patients undergoing
- smooth muscle
- poor prognosis
- oxidative stress
- surgical site infection
- optical coherence tomography
- neoadjuvant chemotherapy
- randomized controlled trial
- coronary artery disease
- ultrasound guided
- clinical trial
- percutaneous coronary intervention
- atrial fibrillation
- radiation therapy
- binding protein
- cell migration
- nk cells