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Prediction of CYP2D6 phenotype from genotype across world populations.

Andrea GaedigkKatrin SangkuhlMichelle Whirl-CarrilloTeri E KleinJames Steven Leeder
Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2016)
This comprehensive study summarizes allele frequencies, diplotypes, and predicted phenotype across major populations, providing a rich data resource for clinicians and researchers. Challenges of phenotype prediction from genotype data are highlighted and discussed.Genet Med 19 1, 69-76.
Keyphrases
  • electronic health record
  • big data
  • genetic diversity
  • machine learning