James Steven Leeder (Bhagwat Prasad, J Steven Leeder)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 31

Top Venues

Clinical pharmacology and therapeutics

Drug metabolism and disposition: the biological fate of chemicals

Clinical and translational science

Genes

Children’s Mercy Hospital

University of Toronto (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Children’s Mercy Hospital

United States

Deputy Director :: Children’s Research Institute

Education History

University of Toronto Sep 01 1984 - May 15 1989

Canada

PHD :: Pharmacology

Publications

Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Aarzoo Thakur, Guihua Yue, Deepak S Ahire, Vijaya S Mettu, Abrar Al Maghribi, Kaitlyn Ford, Lucia Peixoto, James Steven Leeder, Bhagwat Prasad
Sex and the Kidney Drug-Metabolizing Enzymes and Transporters: Are Preclinical Drug Disposition Data Translatable to Humans? Clinical pharmacology and therapeutics 116 (1) (2024)
Kathryn E Kyler, Andrea Gaedigk, Susan M Abdel-Rahman, Vincent S Staggs, Robin E Pearce, Paul Toren, James Steven Leeder, Valentina Shakhnovich
Influence of novel CYP2C-haplotype on proton pump inhibitor pharmacokinetics in children. Clinical and translational science 17 (4) (2024)
Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Aarzoo Thakur, Guihua Yue, Deepak S Ahire, Vijaya S Mettu, Abrar Al Maghribi, Kaitlyn Ford, Lucia Peixoto, James Steven Leeder, Bhagwat Prasad
Sex and the Kidney Drug-Metabolizing Enzymes and Transporters: Are Preclinical Drug Disposition Data Translatable to Humans? Clinical pharmacology and therapeutics (2024)
Aarzoo Thakur, Guihua Yue, Deepak S Ahire, Vijaya S Mettu, Abrar Al Maghribi, Kaitlyn Ford, Lucia Peixoto, James Steven Leeder, Bhagwat Prasad
Sex and the Kidney Drug-Metabolizing Enzymes and Transporters: Are Preclinical Drug Disposition Data Translatable to Humans? Clinical pharmacology and therapeutics 116 (1) (2024)
Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Kathryn E Kyler, Andrea Gaedigk, Susan M Abdel-Rahman, Vincent S Staggs, Robin E Pearce, Paul Toren, James Steven Leeder, Valentina Shakhnovich
Influence of novel CYP2C-haplotype on proton pump inhibitor pharmacokinetics in children. Clinical and translational science 17 (4) (2024)
Shen Cheng, Mahmoud Al-Kofahi, James Steven Leeder, Jacob T Brown
Population Pharmacokinetic Analysis of Atomoxetine and its Metabolites in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder. Clinical pharmacology and therapeutics 115 (5) (2024)
Md Masud Parvez, Aarzoo Thakur, Aanchal Mehrotra, Stephani L Stancil, Robin E Pearce, Abdul Basit, James Steven Leeder, Bhagwat Prasad
Age-Dependent Abundance of CYP450 Enzymes Involved in Metronidazole Metabolism: Application to Pediatric PBPK Modeling. Clinical pharmacology and therapeutics (2024)
Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Kathryn E Kyler, Andrea Gaedigk, Susan M Abdel-Rahman, Vincent S Staggs, Robin E Pearce, Paul Toren, James Steven Leeder, Valentina Shakhnovich
Influence of novel CYP2C-haplotype on proton pump inhibitor pharmacokinetics in children. Clinical and translational science 17 (4) (2024)
Shen Cheng, Mahmoud Al-Kofahi, James Steven Leeder, Jacob T Brown
Population Pharmacokinetic Analysis of Atomoxetine and its Metabolites in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder. Clinical pharmacology and therapeutics 115 (5) (2024)
Kathryn E Kyler, Andrea Gaedigk, Susan M Abdel-Rahman, Vincent S Staggs, Robin E Pearce, Paul Toren, James Steven Leeder, Valentina Shakhnovich
Influence of novel CYP2C-haplotype on proton pump inhibitor pharmacokinetics in children. Clinical and translational science 17 (4) (2024)
Pablo Zubiaur, James Steven Leeder, Francisco Abad-Santos, Andrea Gaedigk
Response to "What is the Current Clinical Impact of the CYP2C:TG Haplotype?" Clinical pharmacology and therapeutics (2023)
Shen Cheng, Mahmoud Al-Kofahi, James Steven Leeder, Jacob T Brown
Population Pharmacokinetic Analysis of Atomoxetine and its Metabolites in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder. Clinical pharmacology and therapeutics (2023)
Stephani L Stancil, Robin E Pearce, Vincent S Staggs, James Steven Leeder
Ontogeny of Scaling Factors for Pediatric PBPK Modeling and Simulation: Cytosolic Protein Per Gram of Liver. Drug metabolism and disposition: the biological fate of chemicals (2023)
Pablo Zubiaur, Paula Soria-Chacartegui, Erin C Boone, Bhagwat Prasad, Jean Dinh, Wendy Y Wang, Santiago Zugbi, Andrea Rodríguez-Lopez, Eva González-Iglesias, James Steven Leeder, Francisco Abad-Santos, Andrea Gaedigk
Impact of CYP2C:TG haplotype on CYP2C19 substrates clearance in vivo, protein content and in vitro activity. Clinical pharmacology and therapeutics (2023)
Rose Gelineau-Morel, Christopher Smyser, James Steven Leeder
Identifying Effective Treatments for Dystonia in Patients with Cerebral Palsy: A Precision Therapeutics Approach. Neurology (2023)
Shen Cheng, Mahmoud Al-Kofahi, James Steven Leeder, Jacob T Brown
Population Pharmacokinetic Analysis of Atomoxetine and its Metabolites in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder. Clinical pharmacology and therapeutics (2023)
Chad A Bousman, James M Stevenson, Laura B Ramsey, Katrin Sangkuhl, J Kevin Hicks, Jeffrey A Mills, Ajeet B Singh, Gualberto Ruaño, Daniel J Mueller, Evangelia Eirini Tsermpini, Jacob T Brown, Gillian C Bell, James Steven Leeder, Andrea Gaedigk, Stuart A Scott, Teri E Klein, Kelly E Caudle, Jeffrey R Bishop
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin Reuptake Inhibitor Antidepressants. Clinical pharmacology and therapeutics (2023)
Andrew C Behrle, Justin Douglas, James Steven Leeder, Leon van Haandel
Isolation and Identification of 3,4-Seco-Solanidine-3,4-dioic acid (SSDA) as a Urinary Biomarker of Cytochrome P450 2D6 (CYP2D6) Activity. Drug metabolism and disposition: the biological fate of chemicals (2022)
James Steven Leeder, Andrea Gaedigk, Krista J Wright, Vincent S Staggs, Sarah E Soden, Yvonne S Lin, Robin E Pearce
A longitudinal study of cytochrome P450 2D6 (CYP2D6) activity during adolescence. Clinical and translational science 15 (10) (2022)
Xiaoyan Chu, Bhagwat Prasad, Sibylle Neuhoff, Kenta Yoshida, James Steven Leeder, Dwaipayan Mukherjee, Kunal S Taskar, Manthena V S Varma, Xinyuan Zhang, Xinning Yang, Aleksandra Galetin
Clinical Implications of Altered Drug Transporter Abundance/Function and PBPK Modeling in Specific Populations: An ITC Perspective. Clinical pharmacology and therapeutics 112 (3) (2022)
Brian D Chapron, Alenka Chapron, James Steven Leeder
Recent advances in the ontogeny of drug disposition. British journal of clinical pharmacology (2021)
James Steven Leeder, Jean C Dinh, Andrea Gaedigk, Vincent S Staggs, Bhagwat Prasad, Robin E Pearce
Ontogeny of Scaling Factors for Pediatric PBPK Modeling and Simulation: Microsomal Protein Per Gram of Liver. Drug metabolism and disposition: the biological fate of chemicals (2021)
Deepak S Ahire, Abdul Basit, Lisa J Christopher, Ramaswamy Iyer, J Steven Leeder, James Steven Leeder
Interindividual Variability and Differential Tissue Abundance of Mitochondrial Amidoxime Reducing Component Enzymes in Humans. Drug metabolism and disposition: the biological fate of chemicals 50 (3) (2021)
Stephani L Stancil, Whitney Nolte, Robin E Pearce, Vincent S Staggs, James Steven Leeder
The impact of age and genetics on naltrexone biotransformation. Drug metabolism and disposition: the biological fate of chemicals (2021)
James Steven Leeder
Who Believes They Are "Just Average": Informing the Treatment of Individual Patients Using Population Data. Clinical pharmacology and therapeutics 106 (5) (2019)
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri E Klein, James Steven Leeder
Prediction of CYP2D6 phenotype from genotype across world populations. Genetics in medicine : official journal of the American College of Medical Genetics 19 (1) (2016)

James Steven Leeder.css-eqlu8i{font-size:small;padding-left:4px;} (Bhagwat Prasad, J Steven Leeder)

Publication Activity (10 Years)

Top Topics

Top Venues

James Steven Leeder (Bhagwat Prasad, J Steven Leeder)